Effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern in real-world: a literature review and meta-analysisArticle Published on 2022-12-012022-11-16 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Analysis Beta booster vaccination caused Clinical outcome collected Coverage COVID-19 vaccine COVID-19 vaccine effectiveness declined Delta driven by Effectiveness eligibility criteria evaluated Evolution Gamma Hospitalization Infection literature review Meta-analysis meta-regression moderate omicron protective vaccine provided public health public health measures Real-world study SARS-CoV-2 SARS-CoV-2 variant searched severe disease supported vaccination Vaccine variant variants of concern variants of concern. virus VoC VOCs [DOI] 10.1080/22221751.2022.2122582 PMC 바로가기
Using host receptor as a decoy to treat COVID-19: a solution for immune escape?Article Published on 2022-11-082022-11-16 Journal: EMBO Molecular Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 antibodies COVID-19 pandemic Critical dose driven by Efficacy evade host receptor immune Immunity IMPROVE inoculated K18-hACE2 transgenic mice Lung injury Medicine neutralizing antibody omicron pandemic reduce survival target the SARS-CoV-2 the vaccine therapeutic Therapies treat variant variants [DOI] 10.15252/emmm.202216818 PMC 바로가기
Modelling optimal vaccination strategies against COVID-19 in a context of Gamma variant predominance in BrazilArticle Published on 2022-11-022022-11-16 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] accompanied age AZD1222 Brazil circulating variant Coverage COVID-19 death deaths dose driven by Effectiveness Epidemic estimates evaluate evaluated Evidence Gamma group groups Guidance health system immunization immunization strategy implementation increase in inefficient initial International interval Local modelling Older age outcome populations reached reducing required subsequent Support vaccination Vaccination strategy Vaccine vaccine availability Vaccines. variant variants of concern VoC [DOI] 10.1016/j.vaccine.2022.09.082 PMC 바로가기
A novel method to monitor COVID-19 fatality rate in real-time, a key metric to guide public health policyArticle Published on 2022-10-312022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] applied approach changes in COVID-19 Delta driven by early phase Effect Epidemic Epidemics epidemiological data Fatality rate fused Germany high accuracy Infection MONITOR omicron pandemic public health required sensitivity vaccination Vaccine variant [DOI] 10.1038/s41598-022-23138-4 PMC 바로가기
Optimizing the implementation of a participant-collected, mail-based SARS-CoV-2 serological survey in university-affiliated populations: lessons learned and practical guidanceArticle Published on 2022-10-122022-11-15 Journal: BMC Public Health [Category] COVID19(2023년), SARS, 진단, [키워드] antibody applicability approach Blood change distribution driven by enrolled Epidemiologic methods feasibility Field epidemiology Future Guidance highlight identify implementation Laboratory Massachusetts Pathogens pre-symptomatic Prevalence recruitment Research SARS-CoV-2 SARS-CoV-2 antibody serological survey serological test serology Serosurveys. Spread stratified Study design Study participants subclinical infection symptomatic individual USA utility virus [DOI] 10.1186/s12889-022-14234-1 PMC 바로가기
The interplay between the airway epithelium and tissue macrophages during the SARS-CoV-2 infectionArticle Published on 2022-10-062022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] 3D cultures activate added Air-liquid interface air-liquid interface (ALI) airway airway epithelium Antigen presentation antiviral immune response basolateral side cell type co-culture Contact Course Culture cytokine production cytokine release demonstrated driven by epithelial epithelial cells evaluate HAE hMDM hMDMs Human airway epithelium human airway epithelium (HAE) human monocyte-derived macrophage immune response in viral infected cell Infection Innate immunity lung Macrophage macrophages macrophages. phagocyte primary human airway recruitment Replication SARS-CoV-2 SARS-COV-2 infection Spread the SARS-CoV-2 tissue macrophage transfer virus virus replication [DOI] 10.3389/fimmu.2022.991991 PMC 바로가기
Prepandemic Alzheimer Disease Biomarkers and Anxious-Depressive Symptoms During the COVID-19 Confinement in Cognitively Unimpaired AdultsArticle Published on 2022-10-042022-11-15 Journal: Neurology [Category] 바이오마커, [키워드] 95% CI accelerate Acidic adjust age Alzheimer disease analyses Analysis association Biomarker Biomarkers change changes Clinical prognosis Clinicians Cohort cortical COVID-19 CSF Disease progression driven by expressed family greater HADS Identifier IL-6 Increased independent interleukin-6 investigated Linear regression model majority marker medication MRI multivariable myeloid cell Neuroinflammation Neuropsychiatric Older pandemic participant Participants pathophysiology performed pet protein levels receptor retrospective risk scale Sex smoking Sociodemographic factor Stress stressors structures subset Symptom tested triggering variable women [DOI] 10.1212/WNL.0000000000200948 PMC 바로가기
Statistical and agent-based modelling of the transmissibility of different SARS-CoV-2 variants in England and impact of different interventions영국의 다양한 SARS-CoV-2 변종의 전파 가능성과 다양한 개입의 영향에 대한 통계 및 에이전트 기반 모델링Article Published on 2022-10-032022-09-11 Journal: Philosophical transactions. Series A, Mathematical [Category] COVID19(2023년), SARS, 변종, [키워드] affected agent Agent-based Modelling Alpha B.1.177 calibrated COVID-19 Delta delta variant driven by England English Epidemics estimate example Infection Intervention multivariate regression modelling. prevented reduced Relaxation SARS-CoV-2 epidemic SARS-CoV-2 variant statistical model Transmissibility vaccination viral variant wild type [DOI] 10.1098/rsta.2021.0315 PMC 바로가기 [Article Type] Article
Toward a big picture of COVID-19Article Published on 2022-10-012022-11-15 Journal: Pharmacology Research & Perspectives [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] addition available data benefit caused chronic inflammation clinical trial Corona COVID-19 Critical Culture cybernetics driven by drug eco ecosystem effort ENhance Epidemiology Evidence executive explain explicit Governance handling Inflammation knowledge Laboratory limitation Local lockdown management media mutant National occurred organization pandemic Pandemics pathology Perspective problem reflect Regulation Research SARS-CoV2 suggested System Treatment zoonoses zoonosis zoonosis. [DOI] 10.1002/prp2.996 PMC 바로가기
Circulating multimeric immune complexes contribute to immunopathology in COVID-19Article Published on 2022-09-262022-11-15 Journal: Nature Communications [Category] SARS, 진단, 치료기술, 치료제, [키워드] activating Activation Antiviral circulating comparable contribute COVID-19 COVID-19 progression Critical detrimental disease driven by dysregulated immune response Evidence extreme FcγRs humoral identify IgG IgG response immune complex immunopathology independent Intervention Ligand mitigate paradoxical Patient patients Protective reporter robust SARS-CoV-2 severe COVID-19 SLE specific IgG antibody systemic immune dysregulation systemic lupus erythematosus triggering with mild disease [DOI] 10.1038/s41467-022-32867-z PMC 바로가기